As the Cannabis market grows for medical and recreational use, so does the requirement for standardized quality control within the industry. When it comes to Cannabis quality control there are lots of things to consider, from moisture content to pesticide use.
Moisture Content – Cannabis flower moisture content should be tested and controlled to: minimize the potential risk of mold formation; control microbiological levels; ensure proper drying, curing and storage conditions; and support product life expectancy. Some manufacturing processes for cannabis quality control procedures also demand a certain water content within the starting material.
Terpenoids and Cannabinoids Analysis
The amount of terpenoids and cannabinoids within the starting material determines the best choice industrial processing method and which final cannabis product will likely be manufactured. This analysis is usually completed using LC-MS (Liquid Chromatography Mass Spectrometry) or GC (Gas Chromatography). LC-MS and GC need a flow of inert gas such as hydrogen or nitrogen, both of which can easily be supplied via a gas generator. Uncover more regarding the Peak Scientific selection of gas generators for GC & LC-MS here.
Pesticides and Herbicides – Just like other agricultural crops and products designed for human consumption, Cannabis plants ought to be tested for herbicides and pesticides. Detecting pesticides and herbicides can be tough as a result of complexity of cannabis material. GCMS (Gas Chromatography Mass Spectrometry) is usually used for this purpose.
Microbiological Screening – Medical Cannabis is often utilized for HIV and cancer patients where patient’s immune system continues to be compromised. Therefore, high microbial levels or pathogenic micro-organisms might be deadly. It is important then that several Mycotoxins and fungus types needs to be detected included in cannabis quality control and release specifications.
Residual Solvents – Where solvents happen to be used as an element of Cannabis product processing, solvent residuals within the final products should be tested to make sure that they fulfill the accepted criteria. The FDA has published zvqtob criteria for residual solvents in APIs for pharmaceutical use.
Heavy Metals – Like various other plants, Cannabis draws metals from the earth. It is therfore necessary to test for Mercury, Lead, Arsen and Cadmium.
Cannabinoid Concentration – Concentration ranges for cannabinoids such as THC,THCa, CBD, CBDa, CBN, CBC, CBG should match the ranges specified on the product label, based upon product usage purpose, patient’s condition, age etc. Cannabinoid concentrations can be tested using LC-MS (Liquid Chromatography Mass Spectrometry) and HPLC (Good Performance Liquid Chromatography) . There are a variety of Peak Scientific nitrogen gas generators designed especially for LC-MS, available here.
Terpene Concentration – Terpenes increase cannabinoids’ therapeutic effects and are acknowledged to get their own health advantages, in addition they play a role in Cannabis taste and aroma. They could be detected using GC.
Taking the above into account, it really is clear that you will find a necessity for standarized procedures for all the Cannabis analysis and testing process in order to guarantee safe use. The safest approach to supply cannabis testing laboratories with gas for his or her LC-MS and GC is by gas generators, which tend not to present the safety and health risks related to gas cylinders.